‘Acellular’ first life?
Published: 6 May 2012(GMT+10)
Dr Don Batten engages in an exchange with long-time sceptical correspondent Dr Richard M. (in red) from the United States, who writes in response to Is ATP synthase found in all life? concerning whether or not the hypothetical ‘first life’ needed to be cellular.
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Brian Thomas, along with virtually all other creationists (as well as some evolutionists, unfortunately), makes the tacit but unwavering assumption that there was in the past some entity that they call the “first cell.” This implies a sharp and distinct line between the chemistry of life and of non-life and further that cellularity is a prerequisite for life. This is an assumption, and a shaky one at that. It is much more likely that that this “demarcation line” was instead a broad area in which many configurations came and went before cellularity was well established. We have in the present world instances of acellular organisms, as well as borderline forms such as viruses. Holding up the “first cell” as a prerequisite entity is a ‘straw man;’ other possibilities are readily conceivable and are the subject of scientific investigation.
Maybe the evolutionists who recognize that there must have been a first cell that allowed reproduction are actually correct. You ought to know that viruses are not ‘borderline forms’ of life at all, but are wholly dependent on the panoply of cellular enzymes, ribosomes, tRNAs and cofactors for production of their proteins and replication of their DNA or RNA. Furthermore, even evolutionary virologists are increasingly recognizing that viruses are derived from cellular life; they are not the precursors of life.
Life begets life and no one has ever observed anything to the contrary.
Acellular organisms? Please name one (note: a cell with multiple nuclei is not really ‘acellular’).
Life begets life and no one has ever observed anything to the contrary. Once again the evolutionary paradigm trumps the evidence and conjecture replaces sound science to preserve the belief.
Some time back you said you were a Christian. Christians believe that Jesus was conceived miraculously (virginal conception), so I find it odd that you as a Christian would not believe in the miraculous origin of life but rather defend the idea that it arose naturally. Even atheist Francis Crick acknowledged that it was “almost a miracle” (A single-celled irony).
With kind regards,
I realize that you reject the “RNA world” hypothesis, but it is still a topic of intensive research and has by no means been discarded. (See Forterre , P. and Gribaldo, S.HFSP J. 2007 September; 1(3): 156–168 for a fairly recent review.) As for the status of modern-day viruses, it may be largely a matter of semantics. I agree with your statements regarding the multitude of processes that cells must call into play to help viruses to reproduce-this very fact indicates that viruses are not independently alive in the same way that cells are. However, we have the example of the mimivirus, which does seem to straddle the border between cellular and acellular life, in that it is not totally dependent on the machinery of the amoeba within which it reproduces, but does have independent coding for some of its essential functions. You would consider this to be just more semantics, but its status and its role in the origin of cellular live is a subject of active investigation.
It puzzles me that you exclude, a priori, that “a cell with multiple nuclei is not ‘acellular.’” Why do you make this exclusion? In addition to many types of multinucleate cells, the body contains syncytial tissues with many nuclei (the placenta comes to mind); they are not divided into membrane-separated compartments (a key component of the definition of a cell), and they function as one extended cell. And in response to your invitation to “name one”, I offer the case of the migratory phase of the slime mold Physarum polycephalum. (In fact, it is usually referred to in the literature as the “acellular slime mold.”) It is an independently mobile, metabolizing organism that carries out its functions without being compartmentalized into cells-therefore it is reasonable to call it an acellular organism.
Regarding your last point, it is a huge stretch to compare a diffuse series of events in the distant past, events on both sides of a fuzzy line of demarcation, with the singular event of the conception of a human being (I assume that you believe in the humanity of Jesus as well as his divinity). How this latter event may have occurred I do not know, but I do know that it did not involve a transition from pre-cellular to post-cellular life.
There are plenty of current research programs that are ‘dead in the water’ and wasting precious research dollars. RNA world is one of them. Almost none of the problems outlined by Cairns-Smith have been solved and more problems have been discovered.
Mimivirus is still not on the way to self-sustaining, self-reproducing life. It is a long way short.
‘Acellular’ life? Yes, it is called that, but it is really a misnomer. It is really multi-nucleate life. There is still a cell membrane/cell wall, which is a fundamental problem for the origin of life. I did research on plant cell differentiation where the DNA in the nucleus doubles up as the cells get bigger, measured with fluorescence microscopy (up to 16n). I never published it. Some protists can make their cells bigger by a different strategy: more nuclei. They are all choreographed to divide at exactly the same time, so this is no happenstance. But they are still cells, so this does not in any way make the boundary between life and non-life ‘fuzzy’ at all.
My point about the virginal conception (I’m glad you agree that it happened, and yes, I believe that Jesus was both God and man; God incarnate), seems to have flown right over your head. I was merely drawing out the incongruity of you (possibly) believing in a miraculous birth of Christ but then doing your darndest to defend the non-miraculous origin of all life on earth, something that atheists have to defend ‘tooth and nail’ to remove any thought of a Creator from their thinking. It would be nice if you would side with God occasionally (as in Romans 1) rather than the atheists! The origin of life is an open-and-shut case for intelligent (divine) design.
All the best,
Dear Don, Actually, the problem of a cell membrane is one of the least of the problems, since there are a number of natural mechanisms whereby a small region can be separated from the larger space. By the way, are you aware that there are biologists who dismiss the functionality of the cell membrane in favor of a structured gel that maintains cell selectivity and integrity? While this point of view is ably argued by its proponents, it has never gained much traction. But the dissenters have not been suppressed by the “establishment”.
You said in your reply that “There are plenty of current research programs that are ‘dead in the water’ and wasting precious research dollars.” Perhaps we could add to the ‘RNA world” research the R.A.T.E Project of the ICR. This endeavor consumed hundreds of thousands of dollars of contributors’ money and was supposed to shake the foundations of nuclear physics. As far as I know (and you can correct me with specific citations if I am wrong), none of this work has been published in any reputable journal that is directed to the scientific community. (Please do not raise the usual objection of biased editors, discrimination against creationists, etc.–as your recent editorial pointed out, if a scientific idea has merit and has sufficient evidence to support it, it will eventually be given the credence due to it.) And the ICR continues to spin its wheels in research projects that will go no farther than the community of true believers.
Your comment about my “siding with the atheists” illustrates one of our major differences. And I think that I know why you feel that I am in this position. Here are my comments that may shed some light here. I have been a scientist for almost 50 years. Throughout that time, I have learned how to read and write scientific papers with care and critical thought. I have learned how to design, conduct, and analyze experiments, and I have been rather successful in this career. Most fundamentally, I have learned how (and not just in my own field) to compare experimental results and claims with objective reality. If I encounter a claim that runs contrary to what has been established by many decades (or centuries) of scientific research, my skeptical nature is aroused, and I test the assertion against this background, all the while keeping in mind the possibility that new knowledge may invalidate some of what we held to be well established. This often leads to my “siding with the atheists.” For example, my knowledge of physiology, anatomy, physics, and chemistry leads me to discount the literal truth of Jonah having been swallowed by a great fish and surviving inside it for three days, as the Bible literally asserts. This, I suppose, places me in the atheist camp. So be it.
However, I cannot accept the way of “doing science” that is championed by creationists and other biblical literalists. A scientist who has subscribed to the statement (which you will recognize) that “By definition, no apparent, perceived or claimed evidence in any field, including history and chronology, can be valid if it contradicts the Scriptural record.” is not functioning as a scientist. This person has painted him(or her)self into a corner, wherein it becomes necessary to develop elaborate circumlocutions to explain away the obvious. For example, the Bible clearly asserts that some diseases are caused by demons and evil spirits, and it devotes considerable space to this notion. Suppose some scientist comes along with experimental evidence that demonstrates that bacteria, viruses, and environmental toxins are actually the causative agents. To be consistent with your position, you would have to say that the scientific evidence must be invalid, or you must invent a complicated and tortuous explanation of how such knowledge was present in scripture all along. And here is another area in which this approach to science falls down-it forces one to ignore the well-demonstrated consilience of science. While a creationist proposition may appear valid in one area of science, if it is completely at odds with what is known in other fields, it lacks scientific validity, and this again leads to all sorts of makeshift “repairs” to save the original assertion. Consider some examples from the flood of Noah. It is obvious that there is not enough water in today’s world to cover the highest mountains on earth. So the claim is made that the mountains were not there, or were not nearly as high, prior to the flood. But they are here now, and this necessitates the assertion of high-speed mountain-building; this is buttressed by co-opting the idea of plate tectonics. However, the time scale is all wrong, so “rapid plate tectonics” is invented, ignoring the energetic and thermal problems that this raises. And if the time scale is wrong in other contexts, “accelerated radioactive decay” is asserted, again ignoring the consequent huge thermal and lethal radiation that this occurrence would entail. (Although these problems were temporarily shelved by invoking passages in the old testament about “stretching out the heavens”, apparently an attempt to provide a rationale for ‘volumetric cooling’.) In the area of biology, the proposed time scale would require the speciation of the world’s present fauna from the “kinds” on the ark in the space of a few thousand years, all without the addition of any new biological information, a possibility inconsistent with what we know (from empirical scientific research) about how animal and plant reproduction actually occurs.
It is your view that my skeptical analysis of creationist claims places me on the side of the atheists. It also, however, places me on the side of many Christians who are accomplished scientists (but who are dismissed as “compromisers” in the YEC view.) And it saddens me greatly that the creationist approach to science and biblical literalism virtually invites the ridicule of Christianity by the scientific community.
This reply has taken longer that I had intended and is probably too lengthy. But you raised some issues that are at the crux of the problems that we discuss. I do not expect to change your mind (you have promised that you will not do that regardless of the evidence), but I would like you and other creationists to try to appreciate that my being “on the side of the atheists” is due to a false dichotomy of your (plural) own making.
Just some brief responses (I won’t respond to everything; it would seem that there is little point in doing that, but please don’t take silence as tacit admission that you have a point on any issue; I just have to use my time judiciously).
- Cell membranes? Soap bubbles are not membranes. It is not just a matter of separating one space from another. You should know that. Cells have to control what comes in and out; there is no example of a passive cell that relies on simple diffusion.
- Of course dissenters to particular models of abiogenesis (etc.) are not suppressed if they continue to hold that evolution is still true. However, censorship of anyone who contradicts naturalism is rife in modern day science: See, Not too old to be expelled.
- RATE research was privately funded where the donors knew what the money was being used for; it was not funded by theft of taxpayers’ dollars. It has provided powerful evidence for a biblical time-frame for the earth. Of course there are unanswered questions; that is the nature of all attempts to piece together the past when we only have measurements in the present to work on.
- I could make similar claims about my own experience and knowledge of ‘doing science’. However, we have both been doing experimental science and it is in the area of history that we differ, where no-one can do experiments on what happened in the past (see ‘It’s not science’). I don’t believe it is the evidence that is the problem in our differing understanding of history, but our axioms, where we are starting from. Probably the most important of those is our differing attitudes towards the Bible-as-the-Word-of-God (not just ‘containing’ the word of God)—the authority of Scripture and our respective approaches to hermeneutics.
- You say, “A scientist who has subscribed to the statement (which you will recognize) that ‘By definition, no apparent, perceived or claimed evidence in any field, including history and chronology, can be valid if it contradicts the Scriptural record.’ is not functioning as a scientist. This person has painted him (or her)self into a corner, wherein it becomes necessary to develop elaborate circumlocutions to explain away the obvious.” This reveals an ignorance of epistemology (how we know anything). Let me re-phrase this to make the point: “A scientist who has subscribed to the statement (which you will recognize) that ‘By definition, no apparent, perceived or claimed evidence in any field, including history and chronology, can say anything regarding God or the Bible’ is not functioning as a scientist. This person has painted him (or her)self into a corner, wherein it becomes necessary to develop elaborate circumlocutions to explain away the obvious.” In fact you are constraining the science, not us. Where the evidence suggests natural causes, that’s fine with us. Where it suggests supernatural causes (such as the origin of the universe or life or the diversity of life, mankind, etc.), that’s also fine. But you have bought into ‘scientism’, that supernatural conclusions are excluded, no matter what the evidence. This is atheism, not science. Your faith in the ‘consilience’ of science is misplaced, particularly as it takes no account of the fallenness of scientists and the fallibility of the enterprise, particularly as it tries to deal with history, where conclusions are predetermined by the materialism of the majority of the operators. The existence of any miracles in history means that the assumption of uniformitarianism cannot be correct when it comes to origins; but your ‘science’ is based on this very assumption.
- The primary finds of the RATE group based on helium retention/diffusion have been beautifully confirmed by parallel data on argon.1 Both lines of evidence point to a period of rapid decay in the past and a biblical age for the earth. We can only speculate about the mechanism (recently-published measured variations in the decay of radioisotopes, apparently in synchrony with Sun cycles,2 shows that much is still not known about radioactive decay; this research had quite a problem getting traction because of the ‘standard model’ does not allow for it.).
I once thought as you, doubting the Bible’s early history, so I can understand where you are coming from and I’m afraid that it does make you a compromiser (as I was). Your fresh admission that you don’t believe the story of Jonah underlines the problem. Jesus said,
“An evil and adulterous generation seeks for a sign, but no sign will be given to it except the sign of the prophet Jonah. For just as Jonah was three days and three nights in the belly of the great fish, so will the Son of Man be three days and three nights in the heart of the earth. The men of Nineveh will rise up at the judgment with this generation and condemn it, for they repented at the preaching of Jonah, and behold, something greater than Jonah is here. (Matthew 12:39–41).
So, Jesus believed that Jonah was swallowed by a ‘great fish’. Was he wrong?
So, Jesus believed that Jonah was swallowed by a ‘great fish’. Was he wrong? One thing that any Christian must do is worship Jesus. How could you worship someone who was so ‘ignorant’ as to believe the story of Jonah? The Bible says that all things were created through Jesus (John 1:1–5). Perhaps you don’t believe in the Resurrection either? You gave your reason for disbelieving the account of Jonah thus: “my knowledge of physiology, anatomy, physics, and chemistry leads me to discount the literal truth of Jonah having been swallowed by a great fish and surviving inside it for three days, as the Bible literally asserts.” It would be entirely consistent for you to say, “My knowledge of physiology, anatomy, physics, and chemistry leads me to discount the literal truth of Jesus having been in the tomb for three days and rising from the dead.” I trust you are indeed inconsistent in this!
But perhaps you are further down the track outlined by Cal Smith than you realize: What all atheists have to believe.
Yours most sincerely,
- Humphreys, D.R., Argon diffusion data support RATE’s 6,000-year helium age of the earth, Journal of Creation 25(2):74–77. Return to text.
- Stober, D., The strange case of solar flares and radioactive elements, August 23, 2010; physorg.com/news201795438.html. Return to text.
As a geologist, a simple one without anything higher than a B.S. degree, working in the oil industry in humble jobs that still gets me dirty with the earth I study, I actually am glad that money is being spent to try to prove this or that to disprove a Theistic way for life and reality. In their spending, they actually do come up with things that have always seemed to be helpful to the Creationist cause...though one needs to disregard the theory part (thanks for the catalogue of weasel words). Of course the downside of being on the unpopular worldview is that we lack the credibility, sometimes to even our Christian peers. That folk are spending money to get into space to find "life," we use their findings to increase our own understanding as God's word encourages us to do. I don't think I could afford these experiments in space, and their desperation just drives them further into the voids of space only to prove that life is NOT there.
The silly statement that the Universe is TOO large to be wasted on life being found on just one dust speck called Earth, ignores the simple fact that the vastness of the Universe only but increases the grandeur of the Creator…one that is said to fill it and even envelope it.
There is one line toward the end of Richard's last reply that, to me, seems to explain a lot. Richard states, "And it saddens me greatly that the creationist approach to science and biblical literalism virtually invites the ridicule of Christianity by the scientific community". Based on this statement, I think Richard (and most other Christian scientists with his mindset) likely rejects Biblical creationism merely out of the fear of ridicule. Now THAT is sad! The logical inconsistencies and irrationality of some of his arguments makes this seem rather clear. For instance, he claims that it is a 'shaky assumption' to hold that there is a sharp distinction between life and non-life, and that the first living thing had to be a cell. Then he goes on to make far shakier and grander assumptions about abiogenesis, which merely begs a hundred other questions. He criticizes CMI for having an a priori commitment to the authority of Scripture, but has no problem with his own a priori commitment to naturalistic scientism. I suspect his statement about the Bible attributing diseases to demonic possession was disingenuous, as it clearly makes no such generalized statements.
Ridicule is nothing to be afraid of. It is merely what unthinking people do when they have run out of answers. Ridicule is used to rouse the emotions and make one's opponent mad. It has no argumentative merit, and is merely a diversionary tactic used to intimidate those with whom the ridiculer disagrees. If the best the 'scientific community' can do is ridicule it's dissenters, then that doesn't say much for the scientific community. The best thing to do when faced with ridicule is to simply smile politely and turn away.
Luke 21:17 [Jesus:] "You will be hated by all for my name's sake."
I have conducted a literature review for the origins of life for a research grant proposal and found that the cell membrane puzzle is extremely close to being solved. For instance, it is hypothesized that montmorillonite could have been used as a catalyst for the first biochemical reactions. This same clay has been shown to lead to membrane formation.
Also, on a side note, if you believe that the search for the origin of life is a "waste of research dollars" then perhaps you should stop opposing it. I hope that you realize that attacking science only justifies our search for the origin of life in order teach the world that there is an answer to this puzzle aside from religous belief.
I suggest you expand your literature review to include the criticisms of the ideas, because this is just so far from explaining the problem as to be laughable, I'm sorry. No one who knows anything about real-world membranes could honestly suggest that clay explains how they formed. As I said, membranes are not just passive barriers; they are full of active protein-based transport channels that use energy to transport things in and out of the cell.
I note also the words you used: "close to being solved" (i.e., not solved, but a huge exaggeration anyway); "hypothesized" (not demonstrated); "could have been" (not demonstrated). "This clay has been shown to lead to membrane formation." "Lead to"? Weasle words. No cell membranes have been formed by clay. If it had happened it would have been shouted from the rooftops. Look up "clay origin of life" on creation.com for a heads up of the debate amongst evolutionists themselves.
None of this game playing explains the formation of real membranes or even begins to explain the information coded on the DNA of the simplest possible free-living cell; see How simple can life be?.
I note also your religious motivation for wasting taxpayers' dollars on origin of life research: to find an answer to the puzzle other than accepting that God created life. So, US government funded origin of life research, by your own admission, contravenes the clear intention of the First Amendment because it involves state-financed opposition to "religion" (Christianity).
Jesus was not wrong.
Jonah was metaphorically in the whale and the Son of Man would metaphorically be in 'the heart of the earth'.
Well done CMI for printing Richard's last message. Study it carefully Don and Calvin, and don't try to discredit scientific method by playing games with words like "supernatural"
Metaphor? See Jonah chapter 2. Jonah was a metaphor? The great fish was a metaphor? Being swallowed by the fish was a metaphor? Jonah's prayer to God was a metaphor? Jonah's being vomited out by the fish onto a beach was a metaphor? His preaching to Nineveh was a metaphor? These were just as real as Jesus' death, burial and resurrection.
Who is playing games? See Games some people play. Misusing 'science' to justify materialism is just that, misuse.
Dear Dr. Batten,
Your patience is astonishing. You take after your Father in that way.
This fellow Richard appears to be intentionally attempting to waste your time, which you have turned to some use by posting as instruction for the rest of us. It actually makes me angry to read his ill thought out excuses for calling God a liar, which he does by denying God's written word about Jonah and all the rest.
I would counsel not to spend more time after the second admonition. Obviously, do as the Holy Spirit leads you. Thank you for your diligence in ministry.
Just a note of encouragement. I think your responses to the gentleman have been quite fair, to the point, and to truth as can be achieved with present knowledge.
We who trust God may not know everything but we do know we can trust Jesus' WORD ... particularly when Jesus speaks so clearly on some subjects. I loved your reply re Jesus actually saying Jonah re the whale, three days, and same will happen in the last days. I trust it struck a cord in the heart and soul of that same gentleman. May it comfort him to know he can't pick and chose to make compromises acceptable.
"The heart is deceitfully wicked."
OH HOW SAD BUT TRUE.
Most kindest regards,
Dr Col., Lismore
Yes, it's well to remember that it is true of all of us!
The correspondent takes a naturalistic approach to Jonah, but the story itself says that "God prepared a great fish". So the scripture makes an explicit statement that overrides naturalistic assumptions, unless you presuppose that God cannot do anything. Preparing the fish must include ensuring that Jonah could survive inside it and also directing it to the particular beach where God wanted Jonah to land.
I almost feel like crying reading the story of another Christian who chooses something else over the clear teaching of God's word.
Oh the need for prayer and continuing to stand for and speak the Truth.
A further comment on Jonah: Dr Richard M wrote that the Bible "literally asserts" that Jonah was alive for the three days he was inside the 'great fish'. Nowhere does the Bible explicitely state that Jonah remained alive during this time. In fact it can be argued from the text in Jonah Ch.2 that he died - and therefore was raised to life three days later. (There are Bible scholars who hold to this view.) This would fit in with Christ's use of the event as a type of his own death and resurrection.
This view is rather unusual and I believe inconsistent with the text: Jonah 2:1 Then Jonah prayed to the LORD his God from the belly of the fish ... [dead men don't pray!] Jonah 2:7 "When my life was fainting away, I remembered the LORD, and my prayer came to you, into your holy temple." Jonah 2:10 And the LORD spoke to the fish, and it vomited Jonah out upon the dry land.
The clear implication is that God saved Jonah before his life fainted away. And surely such a miracle as the resurrection of Jonah would have been specifically recorded?
Furthermore, Jesus' words do not even hint that Jonah died; He only compared the three days: Matthew 12:40 "For just as Jonah was three days and three nights in the belly of the great fish, so will the Son of Man be three days and three nights in the heart of the earth."
So, I think Dr M. was correct that the Bible does teach that Jonah was in the belly of the fish for three days.
It is so clear in this back-and-forth letter discusssion the worship the "scientist" has of science, and his extreme faith in his physical and mental ability to understand the world through his senses. I am concerned that, as he grows older, he may find his body and mind fail him. They will fail him at some time. And then how can he be sure of what is true, if must reason through a fallible vessel? I thank God for His Word of truth, the Bible, which has opened up a greater understanding of this world to me, beyond materialistic atoms and energy, a world He created to have a relationship with me. Thank You Lord Jesus! I pray this writer's eyes are opened, so he may know the great God who created him.I pray he trusts in Jesus more than himself. Thank you CMI for all you do! God Bless you!
Actually, Dr M. is getting near to that latter phase of his life. He is not a young man.
The area of origins is so important to the gospel being given an open hearing in our post-Christian world. God's Word has become nothing more than a book of myths to the secular world because many so-called Christians have declared large portions of it to be nothing more. Despite this it has saddened me to find so much hate and disdain expressed between believers. Like many others I have found the acrimonious nature of intercourse amongst Christians incredibly distressing but this article demonstrates this is not necessary. I would like to complement Dr Richard and Dr Don on their preparedness to dialogue in a respectful and constructive way. From my experience this is rare amongst opponents of creation science.