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Dr Matthew Cserhati

Dr Matthew (Matyas) Cserhati

Molecular Biology and software development

Education

  • 2011, University of Szeged, Hungary, Ph.D., Bioinformatics
  • 2010, University of Szeged, Hungary, B.Sc., Software Development
  • 2003, Eötvös Loránd University, M.Sc., Biology

Language certifications

  • Native Hungarian speaker
  • Swedish, Advanced level, complex, oral
  • Dutch, Intermediate level, oral + written
  • German, Intermediate level, oral
  • Norwegian, Intermediate level, written
  • Beginning Greek, Greenville Presbyterian Theological Seminary
  • Hebrew I+II, Greenville Presbyterian Theological Seminary

Professional experience

During his Ph.D. studies, Matthew developed a transcription factor binding site dyad prediction algorithm, with application to crop species at the Biological Research Center in Szeged, Hungary. He also developed a dedicated website for housing haplotype information on candidate drought genes in barley and taught two science courses.

From 2010–2011, he took part in the development of the program OPTIMA in the laboratory of Chemical Kinetics in the Institute of Chemistry at ELTE University, in Budapest. This work involved the estimation of a number of Arrhenius parameters in a number of combustion reactions. He also taught Linux programming as a special course.

From 2011–2013, he worked as a post-doctoral research fellow at the University of Nebraska, Lincoln. The two main projects he was involved with included the analysis of Next-gen sequencing data to discover differentially expressed genes in the green algae, Chlamydomonas reinhardtii due to low carbon concentrations, and the analysis of the regulation of 177 ribosomal protein genes across ~30,000 experiments, representing hundreds of gigabytes of data from the ENCODE project.

From 2013–2017, he worked as a bioinformatics programmer at the University of Nebraska Medical Center. His tasks included the development of the NNTC-DCC database, a browsable, integrated website for storing experimental and clinical data on neuroAIDS patients. He was also involved in the demultiplexing, storage, and analysis of Next-gen sequencing data for wet-lab researchers. Other notable projects included the de novo genome assembly and annotation of ten NCLDV (NucleoCytoplasmic Large DNA Viruses), as well as the application of a motif prediction algorithm to the genomes of modern and archaic humans. He also helped teach a couple courses in bioinformatics.

In 2017 he started an M.A. program at Greenville Presbyterian Theological Seminary.

From 2018–2019, he took part in the prediction and analysis of differentially expressed genes in hepatocellular carcinoma (HCC) in mouse and human at the University of Texas Health Science Center at San Antonio.

From 2010 He performed over 200 translations and interpretation jobs in Hungarian, German, Swedish, Dutch and Norwegian. He was also a member of the American Translators Association and the Nebraska Association for Translators and Interpreters for several years and he led an informal biblical languages club at Grace Orthodox Presbyterian Church in San Antonio, Texas.

In 2001 he helped establish a creation science group in Hungary called the Protestant Creation Research Group. In 2015 he became a member of the Creation Research Society.

Creationist publications and articles (using several pseudonyms)

Book reviews

  • More of Dawkins’ same old tired rhetoric. Review of Outgrowing God by Richard Dawkins
  • O’Micks, J., Taking the bite out of evolution — critical review of Evolution’s Bite by Peter S. Ungar. Journal of Creation 31(3):24-27, 2017.
  • O’Micks, J., Modern science catches up with Neandertal man, a review of The Neanderthals Rediscovered—How modern science is rewriting their story by Dimitra Papagianni and Michael A. Morse. Journal of Creation 32(1):38–42, 2017.
  • O’Micks, J., and Clarey, T., Book Review of Almost Human, the astonishing tale of Homo naledi and the discovery that changed our human story, by Lee Berger and John Hawks. Answers Research Journal 10:187–194, 2017.

Secular publications

  • Cserhati, M., Xiao, P., Guda, C., K-mer-Based Motif Analysis in Insect Species across Anopheles, Drosophila, and Glossina Genera and Its Application to Species Classification, Computational and Mathematical Methods in Medicine vol. 2019, 2019.
  • Cserhati, M., Mooter, M.E., Fan, M., Wicks, B., Xiao, P., Pauley, M., and Guda, C., Motif comparison between human, Neandertals and Denisova. BMC Genomics 19(1):472, 2018 | doi:10.1186/s12864-018-4710-1.
  • Lopez, W., Page, A.M., Carlson, D.J., Ericson, B.L., Cserhati, M.F., Guda, C., and Carlson, K.A., Analysis of immune-related genes during Nora virus infection of Drosophila melanogaster using next generation sequencing. AIMS Microbiology 4(1):123–139, 2018. doi: 10.3934/microbiol.2018.1.123.
  • Cserhati, M., Motif content comparison between monocot and dicot species. Genom Data 3:128–36, 2015 | doi:10.1016/j.gdata.2014.12.006.
  • Pettkó-Szandtner, A., Cserháti, M., Barrôco, R.M., Hariharan, S., Dudits, D., and Beemster, G.T., Core cell cycle regulatory genes in rice and their expression profiles across the growth zone of the leaf. J Plant Res 128(6):953—74, 2015 | doi:10.1007/s10265-015-0754-3.
  • Cserhati, M., Pandey, S., Beaudoin, J.J., Baccaglini, L., Guda, C., and Fox, H.S., The National NeuroAIDS Tissue Consortium (NNTC) Database: an integrated database for HIV-related studies. Database (Oxford) 2015:bav074 | doi:10.1093/database/bav074.
  • Szécsényi, M., Cserháti, M., Zvara, Á., Dudits, D., and Györgyey, J., Monitoring of transcriptional responses in roots of six wheat cultivars during mild drought stress. Cereal Research Communications 41(4):528–538, 2013 | doi:10.1556/CRC.41.2013.4.3.
  • Cserháti, M., Turóczy, Z., Dudits, D., and Györgyey, J., The rice word landscape: a detailed catalogue of the rice motif content in the non-coding regions. OMICS 16(6):334–42, 2012. doi:10.1089/omi.2011.0056.
  • Cserhati, M., Prommute – A promoter mutation simulation for modeling the evolution of genetic regulatory elements. Journal of Computer Science and Systems Biology 5:74–80, 2012 |doi:10.4172/jcsb.1000093.
  • Brueggeman, A.J., Gangadharaiah, D.S., Cserhati, M., Diaz-Cano, D.C., Weeks, D.P., and Ladunga, I., Activation of the carbon concentrating mechanism by CO2 deprivation coincides with massive transcriptional restructuring in Chlamydomonas reinhardtii. Plant Cell 24(5):1860–75, 2012 | doi:10.1105/tpc.111.093435.
  • Zsély, I.,Gy., Varga, T., Nagy, T., Cserháti, M., Turányi, T., Peukert, S., Braun-Unkhoff, M., Naumann, C., and Riedel, U., Determination of rate parameters of cyclohexane and 1-hexene decomposition reactions. Energy 43(1):85–93, 2012 | doi:10.1016/j.energy.2012.01.004.
  • Turányi, T., Nagy, T., Zsély, I.Gy., Cserháti, M., Varga, T., Szabó, B.T., Sedyó, I., Kiss, P.T., Zempléni, A., and Curran, H.J, Determination of rate parameters based on both direct and indirect measurements. Int J Chem Kinet 44(5):284–302, 2012 | doi:10.1002/kin.20717.
  • Áy, Z., Mihály, R., Cserháti, M., Kótai, É., and Pauk, J., The effect of high concentrations of glufosinate ammonium on the yield components of transgenic spring wheat (Triticum aestivum L.) constitutively expressing the bar gene. The Scientific World Journal 2012:657945 | doi:10.1100/2012/657945.
  • Cseri, A., Cserháti, M., von Korff, M., Bettina, N., Gábor, V.H., Palágyi, A., Pauk, J., Dudits, D., and Törjék, O., Allele mining and haplotype discovery in barley candidate genes for drought tolerance. Euphytica 181:341, 2012 | doi:10.1007/s10681-011-0445-7.
  • Cserháti, M., Turóczy, Z., Zombori, Z., Cserzo, M., Dudits, D., Pongor, S., and Györgyey, J., Prediction of new abiotic stress genes in Arabidopsis thaliana and Oryza sativa according to enumeration-based statistical analysis. Mol Genet Genomics 285(5):375–91, 2011 | doi:10.1007/s00438-011-0605-4.
  • Turóczy, Z., Kis, P., Török, K., Cserháti, M., Lendvai, A., Dudits, D., and Horváth, G.V., Overproduction of a rice aldo-keto reductase increases oxidative and heat stress tolerance by malondialdehyde and methylglyoxal detoxification. Plant Mol Biol 75(4–5):399–412, 2011 | doi:10.1007/s11103-011-9735-7.

Book chapters

  • Cserhati, M., and Gyorgyey, J., “Gene research in silico”, in The science of wheat breeding (ed. Denes Dudits), Winter Fair Ltd., Eger, 2006.
  • Dudits, D., Cserháti, M., Miskolczi, P., and Horváth, G., “The growing family of plant cyclin dependent kinases with multiple functions in cellular and developmental regulation”, in Cell cycle control and development (ed. Dirk Inzé), Blackwell Publishing, Oxford, 2006.

Web Articles

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